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dc.contributor.authorDennis, L.K.
dc.date.accessioned2022-03-18T00:03:58Z
dc.date.available2022-03-18T00:03:58Z
dc.date.issued2022
dc.identifier.citationDennis, L. K. (2022). Cumulative Sun Exposure and Melanoma in a Population‐Based Case–Control Study: Does Sun Sensitivity Matter? Cancers.
dc.identifier.issn2072-6694
dc.identifier.doi10.3390/cancers14041008
dc.identifier.urihttp://hdl.handle.net/10150/663661
dc.description.abstractCutaneous melanoma (CM) has consistently been associated with intermittent sun exposure, while the association with chronic sun exposure is debated. The goal of this research was to examine the complex relationship between CM, sun sensitivity and sun exposure based on theoretical concepts of how these factors may be associated. Detailed sun exposure histories across life periods and various measures of sun sensitivity were collected in a population‐based case–control study of melanoma in Iowa, USA. Participants were asked about their hours of sun exposure per day between March and October each year over periods or decades of life to estimate cumulative lifetime hours of sun exposure. Increased odds ratios (ORs) for CM were seen for most standard measures of sun sensitivity except for the tendency to sunburn. Minimal associations were seen with total hours of sun exposure early in life. However, an interaction was seen between fair skin color and lifetime hours of sun exposure, where the strongest associations with CM were seen among medium‐skinned and dark‐skinned participants. This suggests that cumulative sun exposure at high levels may increase CM among non‐sun‐sensitive individuals typically at lower risk of CM. Such a finding has implications for the prevention effort for melanoma regarding time in the sun among darker‐skinned individuals. © 2022 by the author. Licensee MDPI, Basel, Switzerland.
dc.language.isoen
dc.publisherMDPI
dc.rightsCopyright © 2022 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCumulative sun exposure
dc.subjectCutaneous melanoma
dc.subjectSkin color
dc.subjectSun exposure
dc.subjectSun sensitivity
dc.subjectTotal sun exposure
dc.titleCumulative Sun Exposure and Melanoma in a Population‐Based Case–Control Study: Does Sun Sensitivity Matter?
dc.typeArticle
dc.typetext
dc.contributor.departmentDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona
dc.identifier.journalCancers
dc.description.noteOpen access journal
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
dc.eprint.versionFinal published version
dc.source.journaltitleCancers
refterms.dateFOA2022-03-18T00:03:58Z


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Copyright © 2022 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as Copyright © 2022 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).