Show simple item record

dc.contributor.authorPolo, Manuel Caceres
dc.contributor.authorThibault, Dylan
dc.contributor.authorJawitz, Oliver K
dc.contributor.authorZwischenberger, Brittany A
dc.contributor.authorO'Brien, Sean M
dc.contributor.authorThourani, Vinod H
dc.contributor.authorJacobs, Jeffrey P
dc.contributor.authorHooker, Robert L
dc.date.accessioned2022-03-30T17:45:59Z
dc.date.available2022-03-30T17:45:59Z
dc.date.issued2021-12-04
dc.identifier.citationPolo, M. C., Thibault, D., Jawitz, O. K., Zwischenberger, B. A., O’Brien, S. M., Thourani, V. H., Jacobs, J. P., & Hooker, R. L. (2022). Aortic Prosthetic Valve Endocarditis: Analysis of The Society of Thoracic Surgeons Database. Annals of Thoracic Surgery.en_US
dc.identifier.pmid34875263
dc.identifier.doi10.1016/j.athoracsur.2021.10.045
dc.identifier.urihttp://hdl.handle.net/10150/663804
dc.description.abstractBackground: This study sought to characterize the current US experience of aortic prosthetic valve endocarditis (PVE) compared with native valve endocarditis (NVE). Methods: The Society of Thoracic Surgeons Database was queried for entries of active aortic infective endocarditis (IE). Two analyses were performed: (1) trends of surgical volume and operative mortality (2011-2019); and (2) descriptive and risk-adjusted comparisons between PVE and NVE (2014-2019) using multivariable logistic regression. Results: From 2011 to 2019, there was a yearly increase in the proportion of PVE (20.9% to 25.9%; P <.001) with a concurrent decrease in operative mortality (PVE, 22.5% to 10.4%; P <.001; NVE, 10.9% to 8.5%; P <.001). From 2014 to 2019, active aortic IE was identified in 9768 patients (NVE, 6842; PVE, 2926). Aortic root abscess (50.1% vs 25.2%; P <.001), aortic root replacement (50.1% vs 12.8%; P <.001), homograft implantation (27.2% vs 4.1%; P <.001), and operative mortality (12.2% vs 6.4%; P <.001) were higher in PVE. After risk adjustment, PVE (odds ratio [OR], 1.5; 95% CI,1.16-1.94; P <.01), aortic root replacement (OR, 1.49; 95% CI,1.15-1.92; P <.001), Staphylococcus aureus (OR, 1.5; 95% CI,1.23-1.82; P <.001), and unplanned revascularization (OR, 5.83; 95% CI,4.12-8.23; P <.001) or mitral valve surgery (OR, 2.29; 95% CI,1.5-3.51; P <.001) correlated with a higher operative mortality, whereas prosthesis type (P =.68) was not an independent predictor. Conclusions: IE in the United States has risen over the past decade. However, operative mortality has decreased for both PVE and NVE. PVE, extension of IE requiring aortic root replacement, and additional unplanned surgical interventions carry an elevated mortality risk. Prosthesis selection did not affect operative mortality.en_US
dc.language.isoenen_US
dc.publisherElsevier Inc.en_US
dc.rightsCopyright © 2022 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.en_US
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en_US
dc.titleAortic Prosthetic Valve Endocarditis: Analysis of The Society of Thoracic Surgeons Databaseen_US
dc.typeArticleen_US
dc.identifier.eissn1552-6259
dc.contributor.departmentDepartment of Surgery, University of Arizonaen_US
dc.identifier.journalThe Annals of thoracic surgeryen_US
dc.description.note12 month embargo; published: 04 December 2021en_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal accepted manuscripten_US
dc.source.journaltitleThe Annals of thoracic surgery
dc.source.countryNetherlands


Files in this item

Thumbnail
Name:
ANNALS-21-01184_R1-Resubmissio ...
Embargo:
2022-12-04
Size:
443.9Kb
Format:
PDF
Description:
Final Accepted Manuscript

This item appears in the following Collection(s)

Show simple item record