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dc.contributor.authorKaplan, Deanna M.
dc.contributor.authorMehl, Matthias R.
dc.contributor.authorPace, Thaddeus W. W.
dc.contributor.authorNegi, Lobsang Tenzin
dc.contributor.authorSilva, Brendan Ozawa-de
dc.contributor.authorLavelle, Brooke D.
dc.contributor.authorSivilli, Teri
dc.contributor.authorWilliams, Allison
dc.contributor.authorComstock, Tom
dc.contributor.authorPrice, Bryan
dc.contributor.authorMedrano, Vicente
dc.contributor.authorRobbins, Megan L.
dc.contributor.authorCole, Steven P.
dc.contributor.authorCraighead, W. Edward
dc.contributor.authorRaison, Charles L.
dc.date.accessioned2022-05-13T21:55:42Z
dc.date.available2022-05-13T21:55:42Z
dc.date.issued2022-04-21
dc.identifier.citationKaplan, D. M., Mehl, M. R., Pace, T. W. W., Negi, L. T., Silva, B. O.-D., Lavelle, B. D., Sivilli, T., Williams, A., Comstock, T., Price, B., Medrano, V., Robbins, M. L., Cole, S. P., Craighead, W. E., & Raison, C. L. (2022). Implications of a “Null” Randomized Controlled Trial of Mindfulness and Compassion Interventions in Healthy Adults. Mindfulness.en_US
dc.identifier.issn1868-8527
dc.identifier.doi10.1007/s12671-022-01861-3
dc.identifier.urihttp://hdl.handle.net/10150/664213
dc.description.abstractObjectives: Extensive research suggests that short-term meditation interventions may hold therapeutic promise for a wide range of psychosocial outcomes. In response to calls to subject these interventions to more methodologically rigorous tests, a randomized controlled trial tested the effectiveness of a mindfulness meditation intervention and a compassion meditation intervention against an active control in a demographically diverse sample of medically and psychiatrically healthy adults. Methods: Two hundred and four participants completed a battery of questionnaires to assess psychological experience, participated in a laboratory stress test to measure their biological stress reactivity, and wore the Electronically Activated Recorder (EAR) to assess daily behaviors before and after an eight-week intervention (mindfulness meditation intervention, compassion meditation intervention, or health education discussion group). Results: Neither meditation intervention reliably impacted participants’ subjective psychological experience, biological stress reactivity, or objectively assessed daily behaviors. Furthermore, post hoc moderation analyses found that neither baseline distress nor intervention engagement significantly moderated effects. Conclusions: Results from this trial—which was methodologically rigorous and powered to detect all but small effects—were essentially null. These results are an important data point for the body of research about meditation interventions. Implications of these non-significant effects are discussed in the context of prior studies, and future directions for contemplative intervention research are recommended. Clinical Trial Registry: Registry Number: NCT01643369.en_US
dc.description.sponsorshipFoundation for the National Institutes of Healthen_US
dc.language.isoenen_US
dc.publisherSpringer Science and Business Media LLCen_US
dc.rights© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022.en_US
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en_US
dc.subjectBehavioren_US
dc.subjectCompassionen_US
dc.subjectInflammationen_US
dc.subjectMeditationen_US
dc.subjectMindfulnessen_US
dc.subjectStressen_US
dc.titleImplications of a “Null” Randomized Controlled Trial of Mindfulness and Compassion Interventions in Healthy Adultsen_US
dc.typeArticleen_US
dc.identifier.eissn1868-8535
dc.contributor.departmentDepartment of Psychology, University of Arizonaen_US
dc.contributor.departmentDepartment of Psychiatry, College of Medicine, University of Arizonaen_US
dc.contributor.departmentCollege of Nursing, University of Arizonaen_US
dc.identifier.journalMindfulnessen_US
dc.description.note12 month embargo; published: 21 April 2022en_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal accepted manuscripten_US
dc.identifier.pii1861
dc.source.journaltitleMindfulness


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