Suppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension
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Pulm_circ_2022_Liu_Suppression ...
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Affiliation
Division of Pulmonary, Critical Care and Sleep, Department of Internal Medicine, College of Medicine-Phoenix, University of ArizonaDepartment of Internal Medicine, College of Medicine-Phoenix, University of Arizona
Translational Cardiovascular Research Center, College of Medicine-Phoenix, University of Arizona
Issue Date
2022Metadata
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John Wiley and Sons IncCitation
Liu, B., Yi, D., Pan, J., Dai, J., Zhu, M. M., Zhao, Y.-Y., Oh, S. P., Fallon, M. B., & Dai, Z. (2022). Suppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension. Pulmonary Circulation.Journal
Pulmonary CirculationRights
Copyright © 2022 The Authors. Pulmonary Circulation published by John Wiley & Sons Ltd on behalf of Pulmonary Vascular Research Institute. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
BMP signaling deficiency is evident in the lungs of patients with pulmonary arterial hypertension. We demonstrated that PHD2 deficiency suppresses BMP signaling in the lung endothelial cells, suggesting the novel mechanisms of dysregulated BMP signaling in the development of pulmonary arterial hypertension. © 2022 The Authors. Pulmonary Circulation published by John Wiley & Sons Ltd on behalf of Pulmonary Vascular Research Institute.Note
Open access journalISSN
2045-8932Version
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Except where otherwise noted, this item's license is described as Copyright © 2022 The Authors. Pulmonary Circulation published by John Wiley & Sons Ltd on behalf of Pulmonary Vascular Research Institute. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License.