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Suppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension

dc.contributor.authorLiu, B.
dc.contributor.authorYi, D.
dc.contributor.authorPan, J.
dc.contributor.authorDai, J.
dc.contributor.authorZhu, M.M.
dc.contributor.authorZhao, Y.-Y.
dc.contributor.authorOh, S.P.
dc.contributor.authorFallon, M.B.
dc.contributor.authorDai, Z.
dc.date.accessioned2022-05-19T23:20:14Z
dc.date.available2022-05-19T23:20:14Z
dc.date.issued2022
dc.identifier.citationLiu, B., Yi, D., Pan, J., Dai, J., Zhu, M. M., Zhao, Y.-Y., Oh, S. P., Fallon, M. B., & Dai, Z. (2022). Suppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension. Pulmonary Circulation.
dc.identifier.issn2045-8932
dc.identifier.doi10.1002/pul2.12056
dc.identifier.urihttp://hdl.handle.net/10150/664468
dc.description.abstractBMP signaling deficiency is evident in the lungs of patients with pulmonary arterial hypertension. We demonstrated that PHD2 deficiency suppresses BMP signaling in the lung endothelial cells, suggesting the novel mechanisms of dysregulated BMP signaling in the development of pulmonary arterial hypertension. © 2022 The Authors. Pulmonary Circulation published by John Wiley & Sons Ltd on behalf of Pulmonary Vascular Research Institute.
dc.language.isoen
dc.publisherJohn Wiley and Sons Inc
dc.rightsCopyright © 2022 The Authors. Pulmonary Circulation published by John Wiley & Sons Ltd on behalf of Pulmonary Vascular Research Institute. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License.
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectangiogenesis
dc.subjectBMPR2
dc.subjecthypoxia
dc.subjectpulmonary hypertension
dc.titleSuppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension
dc.typeArticle
dc.typetext
dc.contributor.departmentDivision of Pulmonary, Critical Care and Sleep, Department of Internal Medicine, College of Medicine-Phoenix, University of Arizona
dc.contributor.departmentDepartment of Internal Medicine, College of Medicine-Phoenix, University of Arizona
dc.contributor.departmentTranslational Cardiovascular Research Center, College of Medicine-Phoenix, University of Arizona
dc.identifier.journalPulmonary Circulation
dc.description.noteOpen access journal
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
dc.eprint.versionFinal published version
dc.source.journaltitlePulmonary Circulation
refterms.dateFOA2022-05-19T23:20:14Z


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Copyright © 2022 The Authors. Pulmonary Circulation published by John Wiley & Sons Ltd on behalf of Pulmonary Vascular Research Institute. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License.
Except where otherwise noted, this item's license is described as Copyright © 2022 The Authors. Pulmonary Circulation published by John Wiley & Sons Ltd on behalf of Pulmonary Vascular Research Institute. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License.