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dc.contributor.authorMorrill, K.E.
dc.contributor.authorRobles-Morales, R.
dc.contributor.authorLopez-Pentecost, M.
dc.contributor.authorMartínez Portilla, R.J.
dc.contributor.authorSaleh, A.A.
dc.contributor.authorSkiba, M.B.
dc.contributor.authorRiall, T.S.
dc.contributor.authorAustin, J.D.
dc.contributor.authorHirschey, R.
dc.contributor.authorJacobs, E.T.
dc.contributor.authorSpotleson, L.
dc.contributor.authorHanna, T.P.
dc.date.accessioned2022-08-01T20:17:26Z
dc.date.available2022-08-01T20:17:26Z
dc.date.issued2022
dc.identifier.citationMorrill, K. E., Robles-Morales, R., Lopez-Pentecost, M., Martínez Portilla, R. J., Saleh, A. A., Skiba, M. B., Riall, T. S., Austin, J. D., Hirschey, R., Jacobs, E. T., Spotleson, L., & Hanna, T. P. (2022). Factors associated with cancer treatment delay: A protocol for a systematic review and meta-analysis. BMJ Open, 12(6), e061121.
dc.identifier.issn2044-6055
dc.identifier.pmid35768104
dc.identifier.doi10.1136/bmjopen-2022-061121
dc.identifier.urihttp://hdl.handle.net/10150/665480
dc.description.abstractINTRODUCTION: Treatment delays are significantly associated with increased mortality risk among adult cancer patients; however, factors associated with these delays have not been robustly evaluated. This review and meta-analysis will evaluate factors associated with treatment delays among patients with five common cancers. METHODS AND ANALYSIS: Scientific databases including Ovid MEDLINE, Elsevier Embase, EBSCOhost CINAHL Plus Full Text, Elsevier Scopus and ProQuest Dissertations and Theses Global will be searched to identify relevant articles published between January 2000 and October 2021. Research articles published in the USA evaluating factors associated with treatment delay among breast, lung, prostate, cervical or colorectal adult cancer patients will be included. The primary outcome of the meta-analysis will be the pooled adjusted and unadjusted odds of treatment delay for patient, disease, provider and system-level factors defined according to specified time intervals. The secondary outcomes will be mean or median treatment delay for each cancer site according to first treatment and the influence of factors on the pooled mean treatment delay for each cancer site (via meta-regression analyses). Results from qualitative and mixed-methods studies will be narratively synthesised. Three reviewers will independently screen records generated from the search and two reviewers will independently extract data following a consensus agreement. Statistical heterogeneity will be assessed with a standard I2 test and funnel plots will be conducted to evaluate publication bias. Risk of bias will be assessed independently by two authors using validated tools according to the article's study design. ETHICS AND DISSEMINATION: Formal ethical approval is not required because the work is being carried out on publicly accessible studies. The findings of this review will be disseminated through a peer-reviewed scientific journal, academic conferences, social media, and key stakeholders. PROSPERO REGISTRATION NUMBER: CRD42021293131. © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
dc.language.isoen
dc.publisherBMJ PUBLISHING GROUP
dc.rightsCopyright © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC.
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0
dc.subjectadult oncology
dc.subjectadult surgery
dc.subjectchemotherapy
dc.subjectquality in health care
dc.subjectradiotherapy
dc.titleFactors associated with cancer treatment delay: a protocol for a systematic review and meta-analysis
dc.typeArticle
dc.typetext
dc.contributor.departmentCommunity & Systems Health Science Division, University of Arizona College of Nursing
dc.contributor.departmentDepartment of Clinical and Translational Sciences, University of Arizona College of Medicine
dc.contributor.departmentHealth Sciences Library, University of Arizona
dc.contributor.departmentDivision of Biobehavioral Health Science, University of Arizona College of Nursing
dc.contributor.departmentThe University of Arizona Cancer Center - North Campus
dc.contributor.departmentDepartment of Surgery, University of Arizona College of Medicine
dc.contributor.departmentDepartment of Epidemiology and Biostatistics, University of Arizona
dc.identifier.journalBMJ Open
dc.description.noteOpen access journal
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
dc.eprint.versionFinal published version
dc.source.journaltitleBMJ open
refterms.dateFOA2022-08-01T20:17:26Z


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Copyright © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC.
Except where otherwise noted, this item's license is described as Copyright © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC.