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dc.contributor.authorSohal, Aalam
dc.contributor.authorChaudhry, Hunza
dc.contributor.authorDhaliwal, Armaan
dc.contributor.authorSingla, Piyush
dc.contributor.authorGupta, Gagan
dc.contributor.authorSharma, Raghav
dc.contributor.authorDukovic, Dino
dc.contributor.authorPrajapati, Devang
dc.date.accessioned2022-08-23T20:13:49Z
dc.date.available2022-08-23T20:13:49Z
dc.date.issued2022-08-05
dc.identifier.citationSohal, A., Chaudhry, H., Dhaliwal, A., Singla, P., Gupta, G., Sharma, R., Dukovic, D., & Prajapati, D. (2022). Gender differences in esophageal variceal bleeding in the United States. Annals of Medicine, 54(1), 2115–2122.en_US
dc.identifier.issn0785-3890
dc.identifier.pmid35930410
dc.identifier.doi10.1080/07853890.2022.2104920
dc.identifier.urihttp://hdl.handle.net/10150/665715
dc.description.abstractBackground and Aims: Esophageal variceal bleeding is a common reason for hospitalization in patients with cirrhosis. The main objective of this study was to analyze the effects of gender differences on outcomes in hospitalizations related to Esophageal variceal bleeding in the United States. Methods: A retrospective observational cohort study was performed using the National Inpatient Sample (NIS) database for all hospitalizations with a discharge diagnosis of esophageal varices with hemorrhage from 2016 to 2019. The primary outcome was in-hospital mortality, while secondary outcomes included rate of early endoscopy (defined as less than 1 day), AKI, blood transfusion, sepsis, ICU admission and TIPS (Transjugular Intrahepatic Portosystemic Shunt). We also compared the length of stay and total hospitalization charges. Results: We identified a total of 166,760 patients with variceal bleeding of which 32.7% were females. In-hospital mortality was higher in males, 9.91%, compared to females, 8.31% (adjusted odds ratio (aOR): 0.88, p-value=.008, when adjusted for confounding factors). The odds of undergoing an EGD, length of stay, or total hospitalization charges did not differ between the two groups. Compared to men, women had lower odds of receiving TIPS (aOR = 0.83, p-value=.002). Conclusion: Women hospitalised with esophageal variceal bleeding are at a lower risk of death compared to males. Further research is needed to elucidate the factors associated with this lower risk.en_US
dc.language.isoenen_US
dc.publisherInforma UK Limiteden_US
dc.rights© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/).en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.subjectcirrhosisen_US
dc.subjectdisparitiesen_US
dc.subjectGenderen_US
dc.subjectvariceal bleedingen_US
dc.titleGender differences in esophageal variceal bleeding in the United Statesen_US
dc.typeArticleen_US
dc.identifier.eissn1365-2060
dc.contributor.departmentDepartment of Internal Medicine, University of Arizonaen_US
dc.identifier.journalAnnals of Medicineen_US
dc.description.noteOpen access articleen_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.pii10.1080/07853890.2022.2104920
dc.source.journaltitleAnnals of Medicine
dc.source.volume54
dc.source.issue1
dc.source.beginpage2115
dc.source.endpage2122
refterms.dateFOA2022-08-23T20:13:50Z


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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/).