ACTIVATED IMMUNE MECHANISMS OF THE VETERINARY RATTLESNAKE VACCINE AND ITS DETERMINATION OF ADVERSE REACTIONS IN CANINE PATIENTS

Abstract

This paper examines the information basis behind such wellness decisions regarding administration of the crotalus atrox toxoid in canines based on recurring instances of adverse reactions, such as anaphylaxis, highly attributed to this vaccine. Presentation of previous research conducted on the rattlesnake vaccine as well as case management studies are outlined in the form of a literature review. Additional surveying of veterinary professionals and owners with patients who have experienced hypersensitivity reactions as a result of the vaccine may provide new insights as to potential underlying commonalities. Analysis of the correlation between the rattlesnake vaccine to secondary adverse reactions will follow discussion from a toxicological and immunological perspective. Priorities for research in order to decrease the risk associated with administration of the crotalus atrox toxoid are presented. These findings will hopefully lend more insight into the potential risk factors surrounding the crotalus atrox toxoid as well as pioneer developments in animal health and solutions for addressing a larger spectrum of pre-drug efficacy screening.