LITERATURE REVIEW: THE EFFECTS OF INTERMITTENT FASTING ON METABOLISM AT THE LIVER

Abstract

In recent years, chronic age-related diseases have increased in correspondence with the rising U.S. life expectancy. Metabolic disorders, such as Type II Diabetes, are among such diseases that have increased in prevalence in the aging population. Intermittent fasting has gained traction as preventative and therapeutic measure to prevent metabolic disease. This literature review summarizes the current literature examining the effects of intermittent fasting on lipid metabolism, glycemic control, and insulin sensitivity at the liver. Intermittent fasting improves lipid metabolism and ameliorates hepatic steatosis. Comparatively, the effects of intermittent fasting on glycemic control and insulin sensitivity have conflicting results. These inconsistencies require further examination to reach a consensus on the effects of intermittent fasting on glycemic control and insulin sensitivity.