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    LITERATURE REVIEW: NEUROLOGICAL MECHANISMS THAT UNDERLIE THE THERAPEUTIC POTENTIAL OF THE DISSOCIATIVE COMPOUNDS: KETAMINE, PSILOCYBIN, LSD, AND DMT

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    Author
    SEXAUER, MORGAN RAE
    Issue Date
    2021
    Advisor
    Falk, Torsten
    
    Metadata
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    Publisher
    The University of Arizona.
    Rights
    Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
    Abstract
    Modern research is amidst a psychedelic renaissance characterized by unprecedented growth in understanding the neurological mechanism of psychoactive substances. Given this growth, this review analyzes the known mechanisms of ketamine, psilocybin, lysergic acid diethylamide (LSD), and N, N-Dimethyltryptamine (DMT). A brief introduction to research history is followed by an introduction to diseases these substances have shown promise in alleviating. The impact of these compounds on molecular, cellular, and systems levels is introduced, overlap and differences in their modes of action are highlighted, with concluding statements regarding how effects on these particular levels facilitate therapeutic outcomes. This review should guide future research and serve as a template for synthesizing differences and similarities between substances that profoundly impact consciousness.
    Type
    Electronic thesis
    text
    Degree Name
    B.S.
    Degree Level
    bachelors
    Degree Program
    Neuroscience
    Honors College
    Degree Grantor
    University of Arizona
    Collections
    Honors Theses

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