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    Acute Hospital Outcomes for Renal Transplantation in Patients With Moderate or Severe Congenital Heart Disease

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    Name:
    Renal Transplant CHD - clean.pdf
    Embargo:
    2023-11-05
    Size:
    246.8Kb
    Format:
    PDF
    Description:
    Final Accepted Manuscript
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    Author
    Patel, Surbhi B.
    Webber, Zak
    Strah, Danielle D.
    Hellinger, Riley D.
    Yrun-Duffy, Macken
    Kowalek, Katie A.
    Seckeler, Michael D.
    Affiliation
    College of Medicine, University of Arizona
    Medical Scientist Training Program, College of Medicine, University of Arizona
    Department of Pediatrics, University of Arizona
    Department of Pediatrics (Critical Care), University of Arizona
    Department of Pediatrics (Cardiology), University of Arizona
    Issue Date
    2023-01
    
    Metadata
    Show full item record
    Publisher
    Elsevier BV
    Citation
    Patel, S. B., Webber, Z., Strah, D. D., Hellinger, R. D., Yrun-Duffy, M., Kowalek, K. A., & Seckeler, M. D. (2023). Acute Hospital Outcomes for Renal Transplantation in Patients With Moderate or Severe Congenital Heart Disease. American Journal of Cardiology, 186, 87–90.
    Journal
    American Journal of Cardiology
    Rights
    © 2022 Elsevier Inc. All rights reserved.
    Collection Information
    This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
    Abstract
    Children and adults with congenital heart disease (CHD) are increasingly recognized to be at risk for acute and chronic renal injury. Some of these may progress to the need for renal transplantation. We hypothesized that patients with underlying moderate or severe CHD who undergo renal transplantation will have worse acute hospital outcomes. Using a national administrative database, we queried for admissions aged 0 to 50 years with moderate or severe CHD and renal transplantation and compared these to admissions without CHD. There were 56 admissions for renal transplantation in the CHD group (0.04%) and 26,285 admissions in the group without CHD (0.21%, p<0.001). The CHD group were younger, had a higher proportion of Whites, longer length of stay, higher complication rates, higher in-hospital mortality, and higher costs. In conclusion, although renal transplantation is still relatively uncommon in the CHD population, there is an increasing recognition of severe chronic renal disease in the setting of CHD, making it important to understand the potential implications of these findings.
    Note
    12 month embargo; available online: 05 November 2022
    ISSN
    0002-9149
    DOI
    10.1016/j.amjcard.2022.10.034
    Version
    Final accepted manuscript
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.amjcard.2022.10.034
    Scopus Count
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    UA Faculty Publications

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