Acute Hospital Outcomes for Renal Transplantation in Patients With Moderate or Severe Congenital Heart Disease
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Renal Transplant CHD - clean.pdf
Embargo:
2023-11-05
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Final Accepted Manuscript
Author
Patel, Surbhi B.Webber, Zak
Strah, Danielle D.
Hellinger, Riley D.
Yrun-Duffy, Macken
Kowalek, Katie A.
Seckeler, Michael D.
Affiliation
College of Medicine, University of ArizonaMedical Scientist Training Program, College of Medicine, University of Arizona
Department of Pediatrics, University of Arizona
Department of Pediatrics (Critical Care), University of Arizona
Department of Pediatrics (Cardiology), University of Arizona
Issue Date
2023-01
Metadata
Show full item recordPublisher
Elsevier BVCitation
Patel, S. B., Webber, Z., Strah, D. D., Hellinger, R. D., Yrun-Duffy, M., Kowalek, K. A., & Seckeler, M. D. (2023). Acute Hospital Outcomes for Renal Transplantation in Patients With Moderate or Severe Congenital Heart Disease. American Journal of Cardiology, 186, 87–90.Journal
American Journal of CardiologyRights
© 2022 Elsevier Inc. All rights reserved.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
Children and adults with congenital heart disease (CHD) are increasingly recognized to be at risk for acute and chronic renal injury. Some of these may progress to the need for renal transplantation. We hypothesized that patients with underlying moderate or severe CHD who undergo renal transplantation will have worse acute hospital outcomes. Using a national administrative database, we queried for admissions aged 0 to 50 years with moderate or severe CHD and renal transplantation and compared these to admissions without CHD. There were 56 admissions for renal transplantation in the CHD group (0.04%) and 26,285 admissions in the group without CHD (0.21%, p<0.001). The CHD group were younger, had a higher proportion of Whites, longer length of stay, higher complication rates, higher in-hospital mortality, and higher costs. In conclusion, although renal transplantation is still relatively uncommon in the CHD population, there is an increasing recognition of severe chronic renal disease in the setting of CHD, making it important to understand the potential implications of these findings.Note
12 month embargo; available online: 05 November 2022ISSN
0002-9149Version
Final accepted manuscriptae974a485f413a2113503eed53cd6c53
10.1016/j.amjcard.2022.10.034