Endothelial PHD2 deficiency induces nitrative stress suppression of caveolin-1 in pulmonary hypertension
Affiliation
Division of Pulmonary, Critical Care and Sleep, Dept of Internal Medicine, University of ArizonaCollege of Medicine-Phoenix, University of Arizona
Issue Date
2022-12-22Metadata
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European Respiratory SocietyCitation
Liu, B., Peng, Y., Yi, D., Machireddy, N., Dong, D., Ramirez, K., Dai, J., Vanderpool, R., Zhu, M. M., Dai, Z., & Zhao, Y.-Y. (2022). Endothelial PHD2 deficiency induces nitrative stress via suppression of caveolin-1 in pulmonary hypertension. The European Respiratory Journal, 60(6).Journal
European Respiratory JournalRights
Copyright ©The authors 2022. This version is distributed under the terms of the Creative Commons Attribution NonCommercial Licence 4.0.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
Our recently identified novel mouse model (Egln1Tie2Cre, Egln1 encoding prolyl hydroxylase 2 (PHD2)) has obliterative vascular remodelling and right heart failure, making it an excellent model to use in this study to examine the role of nitrative stress in obliterative vascular remodelling.Note
Open access articleEISSN
1399-3003PubMed ID
35798360Version
Final published versionScopus Count
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Except where otherwise noted, this item's license is described as Copyright ©The authors 2022. This version is distributed under the terms of the Creative Commons Attribution NonCommercial Licence 4.0.