An analytic retrospective pretest-posttest design with interventions, used to evaluate the time taken to document drug adverse events at Banner Health Specialty Pharmacy, as well as identifying the top five medications that lead to adverse events to help increase medication awareness

Abstract

Specific Aims: (1) Decrease in the amount of time taken to report adverse events (ADE) at Banner Specialty Pharmacy-Chandler. (2) Identify the top five medications that cause ADE’s in the pharmacy and determine based on reaction type, frequency, and event severity, important drug information that can be given to future and existing patients. Subjects: Adverse events and medications only. Methods: A data document was used to analyze ADE’s taken from Oct 2018 thru May 2020 to identify the top five medications that cause the most ADE’s. Intervention tools, pharmacist template and use of pharmacy techs, were started on Nov. 11th 2020 till March 1st 2021. Pre-intervention period was from July 2020 to October 2020. ADE pre and post intervention groups were compared to note difference in documentation time. Main Results: The total average documentation time for the pre-intervention period was 12.22 min per event (SD=0.83), while the total average documentation time for the post-intervention period was significantly faster at 10.00 min per event (SD=2.68) (p-value=0.032). Humira, Enbrel, Capecitabine, Imbruvica and Sutent were identified at the top 5 medications to cause ADE’s, and no significant difference was noted in severity between groups (p-value= 0.843). Conclusions: Intervention strategies appeared to decrease the documentation time of ADE’s at Banner Specialty Pharmacy-Chandler. Other variables during the intervention period cannot be ruled out. The information regarding the top five medication that cause adverse events at Banner Specialty Pharmacy- Chandler should only be used as a tool to highlight important counseling points for each of these medications.