RETROSPECTIVE REVIEW OF PHYSICAL ACTIVITY AND NUTRITIONAL QUESTIONNAIRE DATA COLLECTED FROM AN EXERCISE INTERVENTION PROGRAM

Abstract

In 2022, Garcia et al. published a study entitled “Can Exercise Training Alter Human Skeletal Muscle DNA Methylation?”. That study found significant evidence that 8-weeks of exercise training altered DNA methylation patterns in skeletal muscle. This paper is a retrospective review of the data collected by the physical activity and nutritional questionnaires used in that study, which had yet to be analyzed. Here, we performed an analysis of the questionnaire data before and after the 8-weeks of exercise training. The retrospective analysis provides complementary findings to the previously published methylation study of Garcia et al. Additionally, this study examines and discusses participant compliance, limitations, and future recommendations for monitoring physical activity and nutritional diet as part of interventional studies.