Hybrid Whale and Gray Wolf Deep Learning Optimization Algorithm for Prediction of Alzheimer’s Disease
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Department of Pharmacology & Toxicology, The University of ArizonaIssue Date
2023-02-24Keywords
Alzheimer’s disease (AD)brain sub regions
deep learning (DL)
metaheuristic optimization techniques
Mini-Mental State Examination (MMSE) score
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Dhakhinamoorthy, C.; Mani, S.K.; Mathivanan, S.K.; Mohan, S.; Jayagopal, P.; Mallik, S.; Qin, H. Hybrid Whale and Gray Wolf Deep Learning Optimization Algorithm for Prediction of Alzheimer’s Disease. Mathematics 2023, 11, 1136. https://doi.org/10.3390/math11051136Journal
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© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
In recent years, finding the optimal solution for image segmentation has become more important in many applications. The whale optimization algorithm (WOA) is a metaheuristic optimization technique that has the advantage of achieving the global optimal solution while also being simple to implement and solving many real-time problems. If the complexity of the problem increases, the WOA may stick to local optima rather than global optima. This could be an issue in obtaining a better optimal solution. For this reason, this paper recommends a hybrid algorithm that is based on a mixture of the WOA and gray wolf optimization (GWO) for segmenting the brain sub regions, such as the gray matter (GM), white matter (WM), ventricle, corpus callosum (CC), and hippocampus (HC). This hybrid mixture consists of two steps, i.e., the WOA and GWO. The proposed method helps in diagnosing Alzheimer’s disease (AD) by segmenting the brain sub regions (SRs) by using a hybrid of the WOA and GWO (H-WOA-GWO, which is represented as HWGO). The segmented region was validated with different measures, and it shows better accuracy results of 92%. Following segmentation, the deep learning classifier was utilized to categorize normal and AD images. The combination of WOA and GWO yields an accuracy of 90%. As a result, it was discovered that the suggested method is a highly successful technique for identifying the ideal solution, and it is paired with a deep learning algorithm for classification. © 2023 by the authors.Note
Open access journalISSN
2227-7390Version
Final Published Versionae974a485f413a2113503eed53cd6c53
10.3390/math11051136
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Except where otherwise noted, this item's license is described as © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.