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dc.contributor.authorDhakhinamoorthy, C.
dc.contributor.authorMani, S.K.
dc.contributor.authorMathivanan, S.K.
dc.contributor.authorMohan, S.
dc.contributor.authorJayagopal, P.
dc.contributor.authorMallik, S.
dc.contributor.authorQin, H.
dc.date.accessioned2024-08-07T19:41:49Z
dc.date.available2024-08-07T19:41:49Z
dc.date.issued2023-02-24
dc.identifier.citationDhakhinamoorthy, C.; Mani, S.K.; Mathivanan, S.K.; Mohan, S.; Jayagopal, P.; Mallik, S.; Qin, H. Hybrid Whale and Gray Wolf Deep Learning Optimization Algorithm for Prediction of Alzheimer’s Disease. Mathematics 2023, 11, 1136. https://doi.org/10.3390/math11051136
dc.identifier.issn2227-7390
dc.identifier.doi10.3390/math11051136
dc.identifier.urihttp://hdl.handle.net/10150/673907
dc.description.abstractIn recent years, finding the optimal solution for image segmentation has become more important in many applications. The whale optimization algorithm (WOA) is a metaheuristic optimization technique that has the advantage of achieving the global optimal solution while also being simple to implement and solving many real-time problems. If the complexity of the problem increases, the WOA may stick to local optima rather than global optima. This could be an issue in obtaining a better optimal solution. For this reason, this paper recommends a hybrid algorithm that is based on a mixture of the WOA and gray wolf optimization (GWO) for segmenting the brain sub regions, such as the gray matter (GM), white matter (WM), ventricle, corpus callosum (CC), and hippocampus (HC). This hybrid mixture consists of two steps, i.e., the WOA and GWO. The proposed method helps in diagnosing Alzheimer’s disease (AD) by segmenting the brain sub regions (SRs) by using a hybrid of the WOA and GWO (H-WOA-GWO, which is represented as HWGO). The segmented region was validated with different measures, and it shows better accuracy results of 92%. Following segmentation, the deep learning classifier was utilized to categorize normal and AD images. The combination of WOA and GWO yields an accuracy of 90%. As a result, it was discovered that the suggested method is a highly successful technique for identifying the ideal solution, and it is paired with a deep learning algorithm for classification. © 2023 by the authors.
dc.language.isoen
dc.publisherMDPI
dc.rights© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAlzheimer’s disease (AD)
dc.subjectbrain sub regions
dc.subjectdeep learning (DL)
dc.subjectmetaheuristic optimization techniques
dc.subjectMini-Mental State Examination (MMSE) score
dc.titleHybrid Whale and Gray Wolf Deep Learning Optimization Algorithm for Prediction of Alzheimer’s Disease
dc.typeArticle
dc.typetext
dc.contributor.departmentDepartment of Pharmacology & Toxicology, The University of Arizona
dc.identifier.journalMathematics
dc.description.noteOpen access journal
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
dc.eprint.versionFinal Published Version
dc.source.journaltitleMathematics
refterms.dateFOA2024-08-07T19:41:49Z


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© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Except where otherwise noted, this item's license is described as © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.