Biosymbiotic Wearable Platform for High-Fidelity Monitoring of Biosignals for Personalized Wound Care

Abstract

Chronic wounds require continuous assessment to ensure timely and effective treatment, yet traditional monitoring methods are limited by intermittent evaluations and the inability to capture real-time wound dynamics. Current solutions for wound monitoring, such as temperature-sensing insoles or pH-sensitive hydrogels, fall short due to their single-parameter focus, limited durability, or need for frequent replacements. In this work, we introduce a fully integrated biosymbiotic wearable device capable of long-term, multi-parameter wound assessment through sensors measuring tissue oxygenation, humidity, and thermal conductivity. The flexible structure of the biosymbiotic device enables comfortable, continuous wear while power management solutions support long-term operation suitable for continuous physiological monitoring and wireless recharging. Validation across benchtop, on-body, and preliminary clinical tests confirms stable and reliable sensor performance over time, demonstrating the ability of the biosymbiotic device to detect early signs of healing complications without direct patient intervention. This biosymbiotic device sets a foundation for real-time, responsive wound care, advancing toward a future of seamless, data-driven healthcare at home and in clinical settings.