WHEY OR NO WAY? EXPLORING THE EFFECT OF WHEY PROTEIN ON KIDNEY HEALTH

Abstract

Whey protein, widely recognized for its superior amino acid profile and high bioavailability, has become a popular dietary supplement among athletes, bodybuilders, and individuals seeking to improve muscle mass and recovery. While its physiological benefits are well documented, concerns have been raised about its potential impact on kidney health, particularly in individuals with preexisting renal conditions. This paper examines the relationship between whey protein consumption and kidney function by exploring physiological mechanisms related to protein metabolism, renal workload, and biomarker changes. A narrative review of the literature, including animal and human studies, was performed to assess the effects of high-protein intake on kidney markers, such as glomerular filtration rate, urinary calcium excretion, and proteinuria. Findings suggest that while high protein diets may transiently increase renal workload in healthy individuals, there is limited evidence linking whey protein intake to long-term kidney damage. In contrast, individuals with chronic kidney disease may be more vulnerable to adverse effects, even with moderate increases in protein intake. Overall, whey protein appears to be safe for healthy individuals when consumed in moderation and, under certain conditions, may offer indirect renal benefits.